Microchip Mimics Human Kidneys to Study Toxicity of Drugs

kidney-on-chipResearchers from University of Michigan and Seoul National University in South Korea have created a microchip for use as a tool to measure the effects of different drugs on living kidney cells. Currently animals are widely used to estimate the toxicity of drugs, but oftentimes they are poor mimics of humans and the human kidneys.

The new chip has two containers between which various compounds can be passed. A polyester membrane with cultured human kidney cells positioned between the containers acts as a miniature kidney, filtering whatever comes through the best it can. Testing involves pushing a drug through the membrane and then analyzing the cells inside the chip to see how well they fared.


About Peter Coffaro 1134 Articles

A growth-driven and strategic executive, Peter Coffaro commands more than 20 years of progressive management success within the medical device industry. As a District Sales Manager for Stryker Orthopaedics, Peter was responsible for managing and directing a regional sales force to achieve sales and profit goals within the Rocky Mountain region. Previously, he was the Director of Sales & Marketing for Amp Orthopedics. In this role, Peter was responsible for planning, developing, and leading all sales and marketing initiatives. Peter is a former orthopedic distributor in the Pacific Northwest. He has also worked with DePuy Orthopaedics as well as Zimmer, and held positions in sales, sales training, and sales management. Peter has an extensive background in organizational development, business development, sales management, negotiating and P&L management. Peter holds a B.S. degree in Biology from Northern Illinois University.

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