New Vascular Grafts to Grow Along with Patient After Surgery

artificial-vesselsSurgical heart reconstructions using graft materials can do amazing things for patients, but in young children they have a serious limitation. The grafts don’t grow along with a growing heart, and so for procedures such as right ventricular outflow tract reconstructions repeat surgeries are required. Now researchers at University of Minnesota are reporting in journal Nature Communications on newly developed “off-the-shelf” vascular grafts that can grow as the tissue they’re connecting develops and matures.

The grafts are made of fibroblasts within a fibrin gel. These were then introduced to nutrients in a bioreactor which also stimulated the grafts mechanically, making them stronger and able to withstand lots of force. The cells were then washed away to produce the final graft that does not trigger an immune response.

By medGadget

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About Peter Coffaro 1136 Articles

A growth-driven and strategic executive, Peter Coffaro commands more than 20 years of progressive management success within the medical device industry. As a District Sales Manager for Stryker Orthopaedics, Peter was responsible for managing and directing a regional sales force to achieve sales and profit goals within the Rocky Mountain region. Previously, he was the Director of Sales & Marketing for Amp Orthopedics. In this role, Peter was responsible for planning, developing, and leading all sales and marketing initiatives. Peter is a former orthopedic distributor in the Pacific Northwest. He has also worked with DePuy Orthopaedics as well as Zimmer, and held positions in sales, sales training, and sales management. Peter has an extensive background in organizational development, business development, sales management, negotiating and P&L management. Peter holds a B.S. degree in Biology from Northern Illinois University.

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