Advertisements

Nanoparticles deliver engineered protein to prevent joint damage

nanoparticle-arthritis-7x4-700x400Researchers at Washington University have developed nanoparticles to treat the inflammation that wears away at joint cartilage in patients with osteoarthritis.

Traditional treatment methods to reduce inflammation involve steroid injections, but the body quickly washes them away, leaving the cells vulnerable to more inflammation.

“I see a lot of patients with osteoarthritis, and there’s really no treatment,” senior author Dr. Christine Pham said, according to the university. “We try to treat their symptoms, but even when we inject steroids into an arthritic joint, the drug only remains for up to a few hours, and then it’s cleared. These nanoparticles remain in the joint longer and help prevent cartilage degeneration.”

The nanoparticles, which are smaller than red blood cells, carry a protein bound to a small interfering RNA molecule. The molecules interfere with the process of inflammation, preventing further damage. Researchers tested the nanoparticles on mice after an injury and saw effects within 24 hours, which lasted for weeks after, according to a study published in theProceedings of the National Academy of Sciences.

By Sarah Faulkner | Drug Delivery

READ MORE

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Materialise Medical Blog

behind the scenes of 3D printing

CB Insights - Blog

Discovering, compiling and sharing orthopedic and medical technology news on a daily basis.

My Knee Your Knee

Knee Replacement Surgery on a Knee Replacement Surgeon

TEDMED Blog

Discovering, compiling and sharing orthopedic and medical technology news on a daily basis.

KevinMD.com

Discovering, compiling and sharing orthopedic and medical technology news on a daily basis.

Page Array – Rock Health

Discovering, compiling and sharing orthopedic and medical technology news on a daily basis.

mobihealthnews

mobihealthnews - the daily mHealth industry monitor. Subscribe for our free weekly e-newsletter!

TechCrunch

Startup and Technology News

Sports Medicine Weekly

Brought to You by Dr. Brian Cole & Steve Kashul

OrthoBuzz

Keeping you up-to-date with orthopaedic news

%d bloggers like this: