Bone infections are often very difficult to treat, and with the rise of MRSA this issue has become only more challenging. A team of researchers from University of Missouri, University of North Carolina at Chapel Hill and North Carolina State University, and Silpakorn University in Thailand has developed a way of making tissue scaffolds that ward off MRSA while promoting natural healing at the site of their implantation.
The structure of the scaffold is made of polylactic acid (PLA), a polymer commonly used in implants. It is bioresorbable and is removed by the body over time. Over the structure a coating of silver ion is applied and stem cells ready to differentiate into bone are added.
The silver ions, already widely used to ward off infections in a variety of medical applications, prevent MRSA from settling in, while the stem cells turn to bone. The PLA structure and silver eventually disappear, leaving nothing but natural tissue.
Image Credit: Medgadget