Scaffolds Covered in Stem Cells and Silver Ions to Prevent Osteomyelitis

matrix-seededBone infections are often very difficult to treat, and with the rise of MRSA this issue has become only more challenging. A team of researchers from University of Missouri, University of North Carolina at Chapel Hill and North Carolina State University, and Silpakorn University in Thailand has developed a way of making tissue scaffolds that ward off MRSA while promoting natural healing at the site of their implantation.

The structure of the scaffold is made of polylactic acid (PLA), a polymer commonly used in implants. It is bioresorbable and is removed by the body over time. Over the structure a coating of silver ion is applied and stem cells ready to differentiate into bone are added.

The silver ions, already widely used to ward off infections in a variety of medical applications, prevent MRSA from settling in, while the stem cells turn to bone. The PLA structure and silver eventually disappear, leaving nothing but natural tissue.

By Medgadget

Image Credit: Medgadget

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About Peter Coffaro 1431 Articles
A growth-driven and strategic executive, Peter Coffaro commands more than 20 years of progressive management success within the medical device industry. As a District Sales Manager for Stryker Orthopaedics, Peter was responsible for managing and directing a regional sales force to achieve sales and profit goals within the Rocky Mountain region. Previously, he was the Director of Sales & Marketing for Amp Orthopedics. In this role, Peter was responsible for planning, developing, and leading all sales and marketing initiatives. Peter is a former orthopedic distributor in the Pacific Northwest. He has also worked with DePuy Orthopaedics as well as Zimmer, and held positions in sales, sales training, and sales management. Peter has an extensive background in organizational development, business development, sales management, negotiating and P&L management. Peter holds a B.S. degree in Biology from Northern Illinois University.

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