Comparison of adverse events rates and hospital cost between customized individually made implants and standard off-the-shelf implants for total knee arthroplasty



This study compares selected hospital outcomes between patients undergoing total knee arthroplasty (TKA) using either a customized individually made (CIM) implant or a standard off-the-shelf (OTS) implant.


A retrospective review was conducted on 248 consecutive TKA patients treated in a single institution, by the same surgeon. Patients received either CIM (126) or OTS (122) implants. Study data were collected from patients’ medical record or the hospital’s administrative billing record. Standard statistical methods tested for differences in selected outcome measures between the 2 study arms.


Compared with the OTS implant study arm, the CIM implant study arm showed significantly lower transfusion rates (2.4% vs 11.6%; P = .005); a lower adverse event rate at both discharge (CIM 3.3% vs OTS 14.1%; P = .003) and 90 days after discharge (CIM 8.1% vs OTS 18.2%; P = .023); and a smaller percentage of patients were discharged to a rehabilitation or other acute care facility (4.8% vs 16.4%; P = .003). Total average real hospital cost for the TKA hospitalization between the 2 groups were nearly identical (CIM $16,192 vs OTS $16,240; P = .913). Finally, the risk-adjusted per patient total cost of care showed a net savings of $913.87 (P = .240) per patient for the CIM-TKA group, for bundle of care including the preoperative computed tomography scan, TKA hospitalization, and discharge disposition.


Patients treated with a CIM implant had significantly lower transfusion rates, fewer adverse event rates, and were less likely to be discharged to a rehabilitation facility or another acute care facility. These outcomes were achieved without increasing costs.

By Steven D. Culler, PhD, Greg M. Martin, MD, Alyssa Swearingen, BA | Arthroplasty Today

Image Credit: ConforMIS


About Peter Coffaro 629 Articles
A growth-driven and strategic executive, Peter Coffaro commands more than 20 years of progressive management success within the medical device industry. As a District Sales Manager for Stryker Orthopaedics, Peter was responsible for managing and directing a regional sales force to achieve sales and profit goals within the Rocky Mountain region. Previously, he was the Director of Sales & Marketing for Amp Orthopedics. In this role, Peter was responsible for planning, developing, and leading all sales and marketing initiatives. Peter is a former orthopedic distributor in the Pacific Northwest. He has also worked with DePuy Orthopaedics as well as Zimmer, and held positions in sales, sales training, and sales management. Peter has an extensive background in organizational development, business development, sales management, negotiating and P&L management. Peter holds a B.S. degree in Biology from Northern Illinois University.

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