Researchers 3D print calcium phosphate graphene scaffolds for bone regeneration

Biomimetic 3D printed CaPG matrix design. Image via Nature.

A team of researchers from Carnegie Mellon University (CMU) and the University of Connecticut (UConn) has 3D printed novel calcium phosphate graphene (CaPG) scaffolds that could be used for bone regeneration applications in the future.

The team sought to develop an alternative to traditional autogenous bone grafts that simply stabilize bone defects and injuries. The study saw the successful fabrication of a 3D bioprinted alternative that supports tissue regeneration at the defect site, and which possesses numerous desirable properties such as osteoinductivity, biological safety, a long shelf-life, and reasonable production costs.

Challenges of 3D printing graphene

While graphene’s lightweight properties, electrical and thermal conductivity, and mechanical strength make it a desirable material for applications within biomedicine, energy generation, and microelectronics, much of graphene’s potential comes from deploying the material in its monolayer form. This therefore presents a significant challenge when trying to utilize the material for 3D printing.

Despite this, progress has been made to harness the material’s potential for additive manufacturing in recent years. For instance, Virginia Tech and Lawrence Livermore National Laboratory (LLNL) have developed a high-resolution 3D printing method that involves the dispersal of graphene within a gel to form a 3D printable resin, and the latter has also worked with the University of California Santa Cruz to produce graphene-based aerogel electrodes for energy storage devices.

Elsewhere, graphene-oxide scaffolds that retain many of the monolayer material’s sought-after properties have been successfully 3D printed by Spain’s Institute of Ceramics and Glass and Aix-Marseille University, and University at Buffalo researchers have developed a 3D printed water-purifying aerogel that could be used within wastewater treatment plants.

Most recently, researchers from the Harbin Institute of Technology 3D printed a graphene-oxide soft robot capable of moving backward and forward on its own when exposed to moisture.

By Hayley Everett | 3D Printing Industry

Image Credit: Nature

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Peter Coffaro is a growth-driven and strategic executive with over 25 years of progressive management success in the medical device industry. With a proven track record and recognized expertise, Peter has established himself as one of the top influencers in medical sales, as acknowledged by prestigious publications such as the World Journal of Orthopedics, Exponential Healthtech, and MedReps.com. Throughout his career, Peter has accumulated 10 years of combined sales management experience, excelling in various roles including Director, General Manager, Distributor, and Vice President. He has worked for industry-leading orthopedic companies such as Zimmer, DePuy, and Stryker, solidifying his deep knowledge and network within the field. Peter’s passion for innovation and emerging technologies led him to found OrthoFeed, an award-winning blog covering digital orthopedic news and emerging medical technologies. Through this platform, he stays at the forefront of the industry and contributes to the dissemination of valuable insights. Peter is a three-time Hall of Fame award winner at Johnson and Johnson, demonstrating his exceptional contributions and impact on the organization. His expertise extends to areas such as organizational development, business development, sales management, digital marketing, and professional education. Peter earned a B.S. degree in Biology and Chemistry from Northern Illinois University, further complementing his comprehensive understanding of the medical field. With his wealth of experience, strategic mindset, and dedication to advancing healthcare, Peter Coffaro is a valuable asset and leader in the medical device industry.

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